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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYN3
All Species:
16.97
Human Site:
S475
Identified Species:
41.48
UniProt:
O14994
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14994
NP_003481.3
580
63303
S475
P
L
S
P
Q
S
G
S
P
Q
Q
Q
R
S
P
Chimpanzee
Pan troglodytes
XP_515096
579
63181
S474
P
L
S
P
Q
S
G
S
P
Q
Q
Q
R
S
P
Rhesus Macaque
Macaca mulatta
XP_001086745
582
63133
L477
K
V
L
P
P
R
R
L
P
P
G
P
S
L
P
Dog
Lupus familis
XP_850873
579
63100
G474
Q
P
L
S
P
P
S
G
S
P
Q
Q
R
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8JZP2
579
63326
S474
P
V
S
P
Q
S
G
S
P
Q
Q
Q
R
S
P
Rat
Rattus norvegicus
O70441
579
63330
S474
P
V
S
P
Q
S
G
S
P
Q
Q
Q
R
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510451
589
64300
S484
P
Q
S
P
Q
S
S
S
P
Q
R
S
P
G
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079204
580
63774
T475
K
A
N
S
L
R
F
T
A
W
L
P
T
D
T
Zebra Danio
Brachydanio rerio
NP_001119909
670
72335
Q564
Q
G
G
P
Q
Q
T
Q
D
A
P
Q
P
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24546
1025
107509
E700
R
V
N
P
F
D
K
E
P
S
K
S
G
S
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
60.6
93.9
N.A.
92.4
92
N.A.
74.8
N.A.
68
52.8
N.A.
27.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
74.2
95.5
N.A.
95.1
95.3
N.A.
82.8
N.A.
79.1
65.9
N.A.
37.7
N.A.
N.A.
N.A.
P-Site Identity:
100
100
20
33.3
N.A.
93.3
93.3
N.A.
53.3
N.A.
0
26.6
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
33.3
N.A.
100
100
N.A.
60
N.A.
13.3
33.3
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
10
10
0
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
10
0
0
0
0
10
0
% D
% Glu:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
10
0
0
0
40
10
0
0
10
0
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
20
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% K
% Leu:
0
20
20
0
10
0
0
10
0
0
10
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
50
10
0
80
20
10
0
0
70
20
10
20
20
0
70
% P
% Gln:
20
10
0
0
60
10
0
10
0
50
50
60
0
0
0
% Q
% Arg:
10
0
0
0
0
20
10
0
0
0
10
0
50
0
0
% R
% Ser:
0
0
50
20
0
50
20
50
10
10
0
20
10
60
10
% S
% Thr:
0
0
0
0
0
0
10
10
0
0
0
0
10
0
10
% T
% Val:
0
40
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _